Bacterial Pathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern at a Private Hospital in Jakarta, Indonesia

Abstract

Urinary Tract Infection (UTI) is the most widespread infectious disease in the world after respiratory tract infection. The incidence of UTI in Indonesia are around 90-100 cases in every 100,000 population per year. UTI is an infection caused by the growth of microorganisms in human urinary tract involving the kidneys, ureters, bladder, and urethra. UTIs are caused by a variety of bacteria, but the 90% incidence of UTI is caused by E. coli. The pattern of the bacteria causing UTI and its antibiotic susceptibility plays an important role in the treatment of UTI. The aims of this study were to isolate and identify bacterial pathogenic agents that causing UTI at a private hospital in Jakarta and to evaluate their antibiotic susceptibility pattern. A total of 121 (29,2 %) from 293 urine samples collected from patients with UTI symptoms showed a positive bacterial cultures which is the 66,1 % were from females and 33,9 % were from males patients. The UTI- causing bacteria which found were E. coli (65,3 %) and Klebsiella pneumoniae (13,2 %). The highest incidence of UTI occured in elder patients (38,8 %). Married patients (89,3%) had a higher incidence of UTI compared with single patients (10,7 %). The antibiotic susceptibility test showed that E.coli isolated from UTI patients was most resistant to amoxicillin and ampicilin (96.05 %) and most susceptible to Piperacilin (98.7 %). KPneumoniae isolated from UTI patients was most resistant to Ampicillin (90,6 %) and most susceptible to Piperacilin (98.83 %).